RNA-binding Motif Protein 45 (Rbm45)/Developmentally Regulated RNA-binding Protein-1 (Drbp1): Association with Neurodegenerative Disorders
نویسندگان
چکیده
منابع مشابه
Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders
The unique biology of RNA binding proteins is altering our view of the genesis of protein misfolding diseases. These proteins use aggregation of low complexity domains (LCDs) as a means to regulate the localization and utilization of RNA by forming RNA granules, such as stress granules, transport granules and P-bodies. The reliance on reversible aggregation as a mechanism for biological regulat...
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Cytoplasmic protein aggregates are one of the pathological hallmarks of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Several RNA-binding proteins have been identified as components of inclusion bodies. Developmentally regulated RNA-binding protein 1 (Drb1)/RNA-binding motif protein 45 is an RNA-binding protein that was ...
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ژورنال
عنوان ژورنال: Journal of Student Research
سال: 2018
ISSN: 2167-1907
DOI: 10.47611/jsr.v7i2.417